Analysis of Gametocyte Carriage at Diagnosis by Site and Malaria Species

Nov 17, 2024, 10:41 PM

Can you visualize the gametocyte carriage data?

How can we interpret the p-values in this context?

In the context of this analysis, the p-value is used to determine the statistical significance of the observed proportion of patients with gametocytes at the time of diagnosis compared to a hypothetical proportion (in this case, 50%). Here's how to interpret the p-values:
  • P-value < 0.05: This indicates that the observed proportion is statistically significantly different from the hypothetical proportion of 50%. In other words, there is strong evidence against the null hypothesis, suggesting that the gametocyte carriage rate is not equal to 50%.
  • P-value >= 0.05: This suggests that there is not enough evidence to reject the null hypothesis, meaning the observed proportion is not significantly different from 50%.
In our analysis:
  • For Birbir - Pf, the p-value is extremely low (3.94e-31), indicating a significant difference from 50%.
  • For Birbir - Pv, the p-value is 0.0129, also indicating a significant difference.
  • For Methara - Pf, the p-value is 7.97e-27, showing a significant difference.
  • For Methara - Pv, the p-value is 2.54e-16, indicating a significant difference.
All these p-values are less than 0.05, suggesting that the gametocyte carriage rates are significantly different from 50% for all groups.

conduct gametocytes carriage i.e percentage of patients having gametocytes at the time of diagnosis -Gameto_D0_d(%,SD,95%CI, and P-value ) by each malaria specious type (Specs) for each site

The table above provides the gametocyte carriage data at the time of diagnosis for each malaria species type (Pf and Pv) at two different sites (Birbir and Methara). Here's a breakdown of the columns:
  • Percentage: The percentage of patients having gametocytes at the time of diagnosis.
  • SD: The standard deviation of the percentage.
  • CI Lower and CI Upper: The lower and upper bounds of the 95% confidence interval for the percentage.
  • P-value: The p-value indicating the statistical significance of the difference from a hypothetical proportion (e.g., 50%).
This data helps in understanding the prevalence and variability of gametocyte carriage across different sites and species types.
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